breast cancer associated with dermatomyositis

نویسندگان

nasim valizadeh

چکیده

dermatomyositis (dm) is a rare idiopathic inflammatory myopathy with characteristic skin lesions. case series have shown an association between dermatomyositis and malignancy. malignancy has been found in 15-25% of the adult patients with dermatomyositis. a 50-year-old new case of breast cancer, was admitted with muscle weakness and inability to walk. physical examination revealed fever, periorbital edema, a heliotrope rash on the upper eyelids, a large right-sided breast mass and erythematous plaques on the upper chest, abdomen and legs. during hospitalization, she developed a nasal speech, dysphasia, and nasal regurgitation of food and water. a clinical diagnosis of dermatomyositis secondary to breast adenocarcinoma was made according to the skin lesions, muscle weakness, elevated esr, and increased cpk and ldh levels. wide spectrum antibiotics and dexamethasone were administered but fever persisted. although chemotherapy was recommended, she developed respiratory failure and aspiration pneumonia and died. dermatomyositis is one of the paraneoplastic syndromes which are associated with breast cancer. although treatment of dermatomyositis generally includes corticosteroids with or without immunosuppressants, cancerdirected specific therapy including surgery and/or chemotherapy would be more effective. dermatomyositis should be considered in breast cancer patients with skin lesions and muscle weakness and cancer-specific therapy should be started as soon as possible.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Breast Cancer Associated with Dermatomyositis

Dermatomyositis (DM) is a rare idiopathic inflammatory myopathy with characteristic skin lesions. Case series have shown an association between dermatomyositis and malignancy. Malignancy has been found in 15-25% of the adult patients with dermatomyositis. A 50-year-old new case of breast cancer, was admitted with muscle weakness and inability to walk. Physical examination revealed fever, perior...

متن کامل

Dermatomyositis associated with breast cancer.

An increased risk of underlying malignancy has been found in patients with dermatomyositis (DM). The risk is increased even in patients with DM aged 45 or younger and remains high for many years after diagnosis. Breast carcinoma does not represent the most common solid tumor associated with this autoimmune disorder. In the present report, two new cases of DM associated with breast cancer are de...

متن کامل

Dermatomyositis Associated with Gallbladder Cancer

Dermatomyositis, an idiopathic inflammatory myopathy with characteristic skin manifestations, is associated with several types of cancer. Only three cases of gallbladder cancer with dermatomyositis have been reported worldwide, and none has been reported in Korea. We present a case of a 71-year-old male with proven dermatomyositis associated with gallbladder cancer to emphasize the necessity of...

متن کامل

Dermatomyositis associated with Pityriasis Rubra Pilaris: A case report

A 9-year old boy had severe muscle weakness and typical skin rash and EMG with diagnosis of dermatomyositis associated with erythrodermia with islands of normal skin and palmoplantar hyperkeratosis, which was reported. As PRP in skin biopsy. Association dermatomyositis with PRP is very rare.

متن کامل

Muscular visualisation on a bone scan in paraneoplastic dermatomyositis associated with breast cancer

Pan African Medical Journal. 2016; 23:9 doi:10.11604/pamj.2016.23.9.7455 This article is available online at: http://www.panafrican-med-journal.com/content/article/23/9/full/ © Abdelhamid Biyi et al. The Pan African Medical Journal ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), ...

متن کامل

Dermatomyositis and Paclitaxel-Induced Cutaneous Drug Eruption Associated with Metastatic Breast Cancer

Dermatomyositis (DM) is an idiopathic autoimmune connective disease characterized by muscles and skin inflammation of and a well-recognized association with several human malignancies, especially breast cancer. Paclitaxel is a taxane antineoplastic agent with therapeutic effects against a wide range of cancers including breast cancer. This drug is well known for neurotoxicity and hypersensitivi...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
iranian journal of blood and cancer

جلد ۱، شماره ۲، صفحات ۷۹-۸۱

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023